CALIBRATION OF pH METER
STANDARD
OPERATING PROCEDURE
|
SUBJECT:
CALIBRATION
OF pH METER
|
DEPARTMENT : QA
SOP
NO. :
XXX
Page
No :
1 of 2
Effective
Date : 28.09.2010
Next
Review : 27 .09.2015
SOP
REVISION : XXX
|
1.0 OBJECTIVE:
To provide guidelines for Calibration of the pH meter.
2.0 POLICY:
To lay down a procedure for Calibration of PH meter.
3.0
PROCEDURE:
3.1 To
standardize the pH meter select two buffer solutions whose difference in pH
does not exceed four units, such that the expected pH of the material under
test falls between them.
3.2 Prepare
the buffer solutions having pH 4, 7, 9.20 & 12.45
3.2.1
Buffer solution
pH 4.0, 7.0, 9.2 are prepared as directed on the instructions of the pack.
3.2.2
Buffer pH 12.45 is prepared as directed in IP-2014 Page. No
169 Section 2.4.24.
3.2.3
Prepare the
buffer solutions on the first working day of the week.
3.3 Switch
“on” the equipment. Remove the
electrode from the water; wipe out the water on the electrode using tissue
paper than rinse the electrode with Carbon di oxide free water than wipe
out with tissue paper.
3.4 Immerse
the electrode in one of the buffer solution, adjust the temperature control and
adjust the calibration control to the observed pH value identical with the
buffer solution under examination, by shaking it slowly.
3.5 Takeout the electrode washed with CO2 free
water, wipe it with tissue paper.
3.6 Repeat the procedure using second buffer
solution.
3.7 Place
the electrode the third buffer solution and check the pH without adjusting the
calibration control at same temperature.
|
PRIME
MOVER CONCURRER APPROVER
G.Devender CH.Visveshwar
Rao
T.Shyam Sunder
EXECUTIVE (Q.A) PRODUCTION MANAGER G.M (Q.A)
|
SOP
No. : 44/QA
Page : 2 of 2
Revision
No : 12
3.8 Note
down the pH readings of the solutions in Calibration register before making
necessary adjustment.
3.9
The readings of all three buffers should
not differ more than 0.05 units of the original units.
Example : pH 4.0 – Range 3.95 to 4.05
pH 7.0
– Range 6.95 to 7.05
pH 9.2
– Range 9.15 to 4.25
pH 12.45
– Range 12.40 to 12.45
3.10 If the
difference is more than 0.05 units examine the electrodes & if they are
faulty, replace the electrode.
4.0 FREQUENCY: Daily.
5.0 RESPONSIBILITY: Executive (QA) / Jr. Executive (QA).
6.0 REVIEW
GUIDE: Calibration Record.
7.0 ANNEXURE:
-------
8.0 SOPs DISTRIBUTION:
This
SOP shall be distributed to following Departments:
|
Name of the Department
|
Master Copy
|
Circulatory Copy
|
|
QA/QC
|
√
|
√
|
|
Production
|
x
|
x
|
|
Warehouse
|
x
|
x
|
|
General
|
x
|
x
|
|
Maintenance
|
x
|
x
|
9.0 REVISION
HISTROY :
|
Revision number
|
Change
|
|
Revision no 10 to 11
|
1.SOP
revised as per due date.
|
|
Revision no 11 to 12
|
1.Point
3.2 amended in SOP.
2.Point
3..2.2 Included in the SOP
|
|
PRIME
MOVER CONCURRER APPROVER
EXECUTIVE (Q.A) PRODUCTION MANAGER G.M
(Q.A)
|
Comments
Post a Comment